Nephrotic Syndrome 1. Definition A glomerular disorder characterized by massive proteinuria (>3.5 g/day) with resulting hypoalbuminemia, edema, and hyperlipidemia. 2. Classic Triad • Proteinuria >3.5 g/day • Hypoalbuminemia (<3 g/dL) • Edema (especially periorbital, dependent) • Hyperlipidemia lipiduria (fatty casts, “Maltese cross” under microscope) 3. Causes (By Age Group) Children • Minimal Change Disease (most common) • Often follows URI or immunization • Responds well to corticosteroids Adu
Nephrotic Syndrome 1. Definition A glomerular disorder characterized …
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