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55:24
Cerebral Edema and Hyperosmolar Therapy
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Hypertonic Solutions 💧 Higher osmolarity than body fluids → water moves out of cells into plasma (cells shrink) Examples in clinical practice: 1. 3% Sodium Chloride (Hypertonic Saline) → used for severe hyponatremia, cerebral edema (reduces brain swelling). 2. 5% Sodium Chloride (rare, severe cases only). 3. Dextrose 10% in Water (D10W) → for severe hypoglycemia, TPN support. 4. Dextrose 20% or 50% (D20W, D50W) → emergency treatment of hypoglycemia. ⚠️ Must be used cautiously → can cause fluid
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