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  1. Nonbenzodiazepine - Wikipedia

    Nonbenzodiazepine pharmacodynamics are similar in mechanism of action to benzodiazepine drugs, acting as GABA A receptor positive allosteric modulators of the benzodiazepine site, …

  2. Anxiolytics, Nonbenzodiazepines: Drug Class, Uses, Side ... - RxList

    Nonbenzodiazepine anxiolytics work on the central nervous system to induce mild sedation and relieve anxiety. Nonbenzodiazepine anxiolytics work by balancing the activity of chemicals …

  3. FDA-Approved Nonbenzodiazepine Receptor Agonists for the Management

    Jan 19, 2017 · Many practitioners and patients are avoiding benzodiazepine receptor agonists (BZDRAs) due to their significant adverse-effect profiles, so pharmacists should understand …

  4. Anxiolytic Medications: Types and Side Effects - WebMD

    Jan 16, 2025 · These have a different structure than benzodiazepines, but they too target GABA in your brain. Non-benzodiazepines are also generally reserved for short-term use.

  5. Benzodiazepines vs. Nonbenzodiazepines - What's the …

    Benzodiazepines and nonbenzodiazepines are both classes of medications commonly used to treat anxiety and sleep disorders. However, they differ in their chemical structure and …

  6. Non-Benzodiazepines: A Comprehensive Guide

    Jun 14, 2025 · Explore the world of non-benzodiazepines, their mechanism of action, and their applications in treating various psychiatric disorders.

  7. Nonbenzodiazepine Sedative-Hypnotics for Sleep Disorders

    Eszopiclone, lemborexant, suvorexant, daridorexant, and zolpidem controlled-release are the only prescription nonbenzodiazepine drugs shown to improve both sleep onset and sleep …

  8. Non benzodiazepines like Zolpidem - Anesthesia General

    Dec 6, 2025 · Non benzodiazepines like zopiclone, Zolpidem, zaleplon and efzopiclone (Z agents) are the newer sedative hypnotic agents which have varied chemical structures. They bind …

  9. Non-benzodiazepines for the treatment of insomnia - PubMed

    Non-benzodiazepines, such as zolpidem, zopiclone and zaleplon, demonstrate hypnotic efficacy similar to that of benzodiazepines along with excellent safety profiles. Non-benzodiazepines …

  10. Medications for anxiety and insomnia: Which is best?

    Aug 16, 2022 · Non-benzodiazepines, also called “Z” drugs, have fewer reports of dependency, abuse potential, rebound insomnia, and interactions with other medications.