Age of onset of amyotrophic lateral sclerosis is modulated by a …
Jan 1, 2013 · Abstract Amyotrophic lateral sclerosis (ALS) is the third most common adult-onset neurodegenerative disease. Individuals with ALS rapidly progress to paralysis and die from …
GWAS Catalog - EMBL-EBI
As of , the GWAS Catalog contains publications, top associations and full summary statistics. GWAS Catalog data is currently mapped to Genome Assembly and dbSNP Build . This …
Age of onset of amyotrophic lateral sclerosis is modulated by a …
Abstract Amyotrophic lateral sclerosis (ALS) is the third most common adult-onset neurodegenerative disease. Individuals with ALS rapidly progress to paralysis and die from …
Causal Inference of Genetic Variants and Genes in Amyotrophic Lateral ...
Jun 22, 2022 · Amyotrophic lateral sclerosis (ALS) is a fatal progressive multisystem disorder with limited therapeutic options. Although genome-wide association studies (GWASs) have …
ALS 2021 GWAS | Knowledge Portal Network
Summary statistics are available for download from the GWAS Catalog. Publications Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with …
Genome-Wide Gene-Set Analysis Approaches in Amyotrophic Lateral Sclerosis
Nov 19, 2022 · The rapid increase in the number of genetic variants identified to be associated with Amyotrophic Lateral Sclerosis (ALS) through genome-wide association studies (GWAS) …
Genome-wide analyses identify NEAT1 as genetic modifier of age …
Oct 23, 2023 · Background Patients with amyotrophic lateral sclerosis (ALS) demonstrate great heterogeneity in the age at onset (AAO), which is closely related to the course of disease. …
Age of onset of amyotrophic lateral sclerosis is modulated by a …
Sep 5, 2012 · Here, we report the results of a meta-analysis of the International Consortium on Amyotrophic Lateral Sclerosis Genetics genome-wide association samples, consisting of 4243 …
Amyotrophic lateral sclerosis (ALS) is a complex disease that leads to motor neuron death. Despite heritabil-ity estimates of 52%, genome-wide association studies (GWASs) have …
The databases of PubMed and Google Scholar were used to identify relevant peer-reviewed papers using the terms “amyotrophic lateral sclerosis”, “GWAS” and “gene-set analysis”.
Genome-wide identification of the genetic basis of amyotrophic lateral ...
Mar 16, 2022 · Amyotrophic lateral sclerosis (ALS) is a complex disease that leads to motor neuron death. Despite heritability estimates of 52%, genome-wide association studies …
Abstract Background Patients with amyotrophic lateral sclerosis (ALS) demonstrate great heterogeneity in the age at onset (AAO), which is closely related to the course of disease. …