Langerhans cells derive from primitive erythro-myeloid progenitors that arise in the yolk sac outside the embryo in the first trimester of pregnancy, and under normal circumstances persist …

Dec 26, 2023 · Langerhans cell histiocytosis (LCH) is a rare disorder that primarily affects babies and children. The disorder occurs when immune system cells called Langerhans cells build up …

Jun 6, 2024 · Langerhans Cell Histiocytosis (LCH) treatment depends on where it is found in the body and whether the LCH is low or high risk. Treatment can include chemotherapy, surgery, …

Langerhans cell histiocytosis (LCH) is a disorder that primarily affects children, but is also found in adults of all ages. People with LCH produce too many Langerhans cells or histiocytes, a form …

Langerhans cells are a type of white blood cell. They play a role in the body’s immune system. Langerhans cells can be found in the skin, lungs, stomach, bones, eyes, and intestines. In …

Apr 26, 2021 · Langerhans cells are a type of immune cell found primarily in the epidermis that have important roles in the stimulation and suppression of the adaptive immune response. …

5 days ago · This review highlights Langerhans cell histiocytosis, the most common subtype, and Rosai-Dorfman disease, a less common non–Langerhans cell histiocytosis entity, using them …

Langerhans cell histiocytosis is a rare, cancer-like condition. Read about causes, symptoms, diagnosis and customized treatment for kids.

Langerhans cells, which help regulate the immune system, are normally found throughout the body, especially in the skin, lymph nodes, spleen, lungs, liver, and bone marrow.

Sep 16, 2025 · Langerhans cell histiocytosis (LCH) is a rare multisystem disease with a wide and heterogeneous clinical spectrum and variable extent of involvement.