Having a supratherapeutic INR while taking warfarin does not significantly increase the risk for brain bleeding after blunt head trauma in older adults.

Cognitive functional therapy, with or without biofeedback, is more effective than usual care for treating patients with chronic disabling low back pain.

Patients undergoing major surgery who experience alcohol withdrawal syndrome and delirium tremens face higher risks for complications.

Childhood maltreatment shared the most polygenic variants (around 10,0000) with ADHD, ASD, MDD, BPD, and schizophrenia.

Exposure to childhood physical or verbal abuse is similarly associated with lower mental well-being during adulthood.

An increased risk for comorbid insomnia and sleep apnea (COMISA) is significantly associated with reduced work ability.

Cardiovascular disease risk prediction is not improved by incorporating measures of anxiety and depression in the AHA’s PREVENT predictors.

Among people with autoimmune conditions, risk for affective disorders, like depression and anxiety, is almost double the general population.

Metabolic syndrome components are tied to young-onset dementia risk, underscoring the need for prevention and management of related health conditions.

The prevalence of disorders of the gut-brain interaction (DGBI) increased from before to after the COVID-19 pandemic.

For older adults with type 2 diabetes, GLP-1 RA use is associated with nonarteritic anterior ischemic optic neuropathy.

The USPSTF recommends screening adults for unhealthy alcohol use and providing brief behavioral counseling interventions for those engaged in risky drinking.