A 60-year-old man with hypertension and bipolar disorder was incidentally found to have small cysts on his kidneys during MRI of the abdomen.

Cardiovascular diseases, principally ischemic heart disease and stroke, have consistently been the leading cause of death worldwide since 1990 and accounted for 19.8 million deaths in 2022 alone.1 ...

The financial assistance policies of some U.S. hospitals now define medical necessity much more restrictively than it has conventionally been understood, as covering only services that are ...

As her patients near the end of life, an infectious disease physician who knows their stories sometimes needs to step out of her proverbial lane to help them assess and achieve their goals of care.

Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular reocclusion may occur after intravenous thrombolysis and may be preventable ...

A 64-year-old man presented with a 5-month history of a painful ulcer of the lateral left ankle. Recently, he had noticed malodorous secretions, increased erythema and edema, and worsening pain.

In 2006, a prospective observational study first showed that physical activity after a colon cancer diagnosis was linked to a decreased risk of recurrence and death.1 Since then, numerous observati ...

To the Editor: The trial by the BALANCE (Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness) investigators (March 13/20 issue)1 provides valuable insights for clinicians, suppo ...

Prenatal genomic sequencing revealed congenital thrombotic thrombocytopenic purpura, enabling immediate plasma therapy. The case highlights the value and ethical complexity of reporting incidental ...

To the Editor: In the Blood Pressure Control Target in Diabetes (BPROAD) trial, Bi et al. (March 27 issue) 1 used the classic design of a prospective randomized trial with an intention-to-treat ...

As health systems confront the social, economic, and political drivers underlying worsening U.S. population health, a new Perspective series examines the extent to which the business of health care ...