Xenon Pharmaceuticals Inc., a neuroscience-focused biopharmaceutical company dedicated to discovering, developing, and delivering life-changing therapeutics for patients in need, has reported its ...

Despite missing the primary endpoint, the novel K V 7 potassium channel opener azetukalner showed benefit in major depressive ...

Xenon Pharmaceuticals XENE reported a loss of 83 cents per share for the first quarter of 2025, narrower than the Zacks Consensus Estimate of a loss of 94 cents. The company had incurred a loss of 62 ...

A tonic-clonic seizure, formerly called a grand mal seizure, is the "classic" type of seizure most people are familiar with. It involves two phases: In the tonic phase, the muscles stiffen and the ...

These seizures, but particularly the 'tonic clonic' events, would last anywhere between five ... with the only indication of what had happened when I entered something known as the 'postictal phase' - ...

About a third of patients experience a so-called stormy phase, characterised by numerous seizures and seizure types, often generalised tonic-clonic and myoclonic seizures, culminating in ...

If you are affected in this way, it may be helpful to create a plan in advance to help others understand how to keep you safe during this phase. The length of time it takes to recover after a ...

The primary evidence for fenfluramine came from Study 1601, a phase 3 ... reductions of 45.9% for non-drop seizures and 48.8% for generalised tonic-clonic seizures. Around 36% of caregivers ...

Sleepiness is common after a tonic-clonic seizure ... and continued to exhibit symptoms of the postictal phase of a seizure. Initially he appeared to be asleep. Eventually he recovered minimal ...

A tonic-clonic seizure involves two distinct phases: Tonic Phase: This phase is characterized by stiffness and posturing of limbs and trunk, often associated with loss of consciousness.

To address this, we obtained exclusive access to the Open Seizure Database and selected a representative dataset of 94 events (42 generalised tonic-clonic seizures ... detection model designed for ...

sEMG can identify the tension during the tonic phase of tonic–clonic seizure, while ACM is able to detect rhythmic patterns of the clonic phase of tonic–clonic seizures. Machine learning techniques, ...