This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

The authors confirm that telomeres in telomerase-positive cells terminate with 5'-ATC in a Pot1-dependent manner, and demonstrate that this principle holds true in telomerase-negative ALT cells as ...

Editor's note: Justin Thomas defeated Andrew Novak with a birdie on the first playoff hole. The RBC Heritage is headed to a hole-by-hole playoff, with Justin Thomas and Andrew Novak tied at 17 ...

PETALING JAYA: T7 Global Bhd ’s wholly-owned subsidiary, Tanjung Offshore Services Sdn Bhd, has secured a five-year appointment as a panel contractor for engineering, procurement, construction ...

Transcription activator-like effector nucleases (TALENs) are programmable nucleases that have entered the clinical stage. Each subunit of the dimer consists of a DNA-binding domain composed of an ...