This contribution is part of the special series of Inaugural Articles by members of the National Academy of Sciences elected in 2016. Contributed by Helen M. Blau, May 15, 2017 (sent for review April ...

aDepartment of Diagnostic and Interventional Radiology, Technical University of Munich, School of Medicine and Health, Klinikum Rechts der Isar, TUM University Hospital, Ismaninger Str. 22, 81675, ...

Mitochondria are fascinating organelles regulating many critical cellular processes for skeletal muscle physiology. Indeed, they play central roles in muscle cell metabolism, energy supply, the ...

In this review, we highlight the cross talk between PVAT and vascular smooth muscle cells and its roles in vascular remodeling and blood pressure regulation. Perivascular adipose tissue (PVAT) is a ...

The impact of circadian disruption on muscle health and aging has been uncovered. A research team at King’s College London (UK) has uncovered the intrinsic and extrinsic effects that circadian ...

Smooth muscle cell migration occurs during vascular development, in response to vascular injury, and during atherogenesis. Many proximal signals and signal transduction pathways activated during ...

"Since the inflammation caused by the stimulus was not treated, it was expected to induce a series of changes in the muscle tissue, leading to an increased predisposition to chronicity. However ...

These improvements were particularly pronounced in mice treated at 12 months of age. Examination of muscle tissue revealed that treated mice had much less scarring (fibrosis) and maintained larger ...

Our findings highlight the potential of targeting Ror and Rev-erb to mitigate muscle health issues caused by circadian disruption. How central and peripheral circadian clocks regulate protein ...