Sickle Cell Disease is a chronic, inherited blood disorder that affects millions of people worldwide. It is best known for causing anaemia, pain episodes, and organ complications, but a lesser ...

New research shows that inflammation levels in women with sickle cell disease are higher during the follicular phase of the ...

Sickle cell disease is an autosomal recessive blood disorder that can lead to anaemia. It is caused by a mutation in the haemoglobin gene, which leads to deformation of red blood cells.

Vertex Pharma's £1.65 million ($2.05 million) gene-editing therapy for sickle cell disease (SCD), Casgevy ... painful attacks that occur when red blood cells become misshapen and block blood ...

Novo Nordisk has doubled down on position in the sickle cell disease ... patients with the disease so oxygen is held onto for longer, reducing the tendency of red blood cells to deform into ...

distorting red blood cell (RBC) shape (‘sickling’), whose extent depends upon the RBC concentration of HbS relative to HbA/HbF. This is lower in heterozygotes (HbAS with SCT) than homozygotes (HbSS ...

Normochromic Describes RBCs that are normal in color, containing the normal amount ofhemoglobin Normochromic cells are seen in anemia following acute blood loss ... SS and SC disease, and ...

A total of 18 male children diagnosed with Sickle Cell Disease (SCD) were initially recruited from the ... vaso-occlusion, hypertension, blood transfusion, or those taking medication were excluded ...