Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States Integrated Molecular Structure Education and Research Center, Northwestern University, Evanston, Illinois ...

IN an earlier investigation 1 it was shown that pea seeds contain a complex of enzymes which catalyse the following series of reactions, I–IV: ...

and 100 mM phosphate buffer solution at pH 7.4. After preincubation at 37°C for 5 min, the metabolic reaction was initiated by adding EA or EB (2.5, 5, 10, 25, 50 or 100 µM). For assay of ...

Carboxylic acids have been shown to be good phosphate bioisosteres (Burke and Lee, 2003; Elliott et al., 2012). Yet phosphonic acids could potentially better-replicate cognate TOP1-DNA substrate ...

Many eukaryotic proteins regulating phosphate (Pi) homeostasis contain SPX domains that are receptors for inositol pyrophosphates (PP-InsP), suggesting that PP-InsPs may regulate Pi homeostasis. Here ...