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Myosin makes the moves to keep cell processes humming along
Biomolecular condensates are distinct molecular communities made of DNA, RNA and proteins that "condense" molecules to key ...
ahajournals.org4d
The SWI/SNF Chromatin Remodeling Complex Regulates Myocardin-Induced Smooth Muscle–Specific Gene Expression
However, little is known about the epigenetic mechanisms that regulate the activity of these complexes. In the current study, we investigated the role of SWI/SNF ATP-dependent chromatin remodeling ...
C&EN7d
Amphiphilic Cationic Triscyclometalated Iridium(III) Complex–Peptide Hybrids Induce Paraptosis-like Cell Death of Cancer Cells via an Intracellular Ca
Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba ...
PNAS7d
Integrative analysis reveals unique structural and functional features of the Smc5/6 complex
Our findings thus provide insights into Smc5/6 structural anatomy and functions. Structural maintenance of chromosomes (SMC) complexes are critical chromatin modulators. In eukaryotes, the cohesin and ...
AlphaGalileo9d
Chd1 uses exit DNA as a molecular brake to regulate chromatin remodeling
This study proposes a new mechanism by which Chd1 senses and responds to DNA unwrapping via EDBL engagement to suppress ...
PNAS21d
Acute chromatin decompaction stiffens the nucleus as revealed by nanopillar-induced nuclear deformation in cells
This research was supported by funding from the Singapore Ministry of Education (RG145/18, RG93/22, and RT3/22 to W.Z.; MOE-MOET32020-0001 to A.L. and W.Z.), Ministry of Healthy [Healthy Longevity ...
C&EN29d
Always on the Move: Overview on Chromatin Dynamics within Nuclear Processes
Non-Commercial (NC): Only non-commercial uses of the work are permitted. Our genome is organized into chromatin, a dynamic and modular structure made of nucleosomes. Chromatin organization controls ...