Biomolecular condensates are distinct molecular communities made of DNA, RNA and proteins that "condense" molecules to key ...

This study proposes a new mechanism by which Chd1 senses and responds to DNA unwrapping via EDBL engagement to suppress ...

Chromatin remodeling ... of ATP, thus capturing the enzyme in action. Methodical data analysis led the researchers to obtain 13 distinct structures of the SNF2H-nucleosome complex at various ...

April 3, 2025) Chromatin remodeling ... of ATP, thus capturing the enzyme in action. Methodical data analysis led the researchers to obtain 13 distinct structures of the SNF2H-nucleosome complex ...

The ATP-Dependent Chromatin-Remodeling Complexes There are 4 different families of SWI-like ATP-dependent chromatin-remodeling complexes: SWI/SNF (switching defective/sucrose nonfermenting), ISWI ...

Serine ADP-ribosylation (ADPr) is a DNA damage-induced post-translational modification catalyzed by the PARP1/2:HPF1 complex. As the list of ... poly-ADPr marks nucleosomes for ALC1-dependent ...

the ISWI chromatin‐remodeling factors CHR11/17, and the conserved subunits of the NuA4 complex TRA1a and TRA1b (TRA1a/1b). MBD9 and TRA1a/1b promote H2A.Z deposition at the whole‐genome level, whereas ...

Interestingly, monomeric actin as well as actin-related proteins (Arps) are found as stoichiometric subunits of a variety of chromatin remodeling ... to DNA is largely dependent upon intricate ...

Covalent modification of histones by histone acetyltransferase, deacetylase, and methyltransferase, as well as by ATP-dependent protein complexes can also lead to chromatin remodeling. In addition ...

Germany The ATP-dependent BRG1/BRM associated factor (BAF) chromatin remodeling complexes are crucial in regulating gene expression by controlling chromatin dynamics. Over the last decade, it has ...

Chromatin assembly involves the combined action of ATP-dependent motor proteins and histone chaperones. Because motor proteins in chromatin assembly also function as chromatin remodeling factors, we ...