A collaborative study from the University of Cologne has uncovered how a key mitochondrial protein, AIFM1 (Apoptosis-Inducing Factor ...

P5CS-containing mitochondria lacked the MICOS complex component MIC60 and ATP synthase subunit ATP5I. Lack of OPA1 disrupted the cristae but did not prevent proline biosynthesis.

The ATP Citrate Synthase-mediated production of acetyl-CoA has significant implications for cellular processes such as lipogenesis, where acetyl-CoA serves as a central building block. Beyond its role ...

We isolate these mitochondrial‐derived vesicles (MDVs) and find that they are relatively uniform in size, of about 100 nm, and carry selective protein cargo enriched for ATP synthase subunits.

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Complex V uses the proton motive force that is generated by the respiratory chain for the synthesis of ATP. The catalytic F 1 domain of complex V consists of a trimer of α−β dimers and a ...

Theoretical research examining the electric field within the energy-making enzyme ATP synthase alludes to it having a much higher enzymatic efficiency than reported in textbooks. 1 Calculations of the ...