Tyree Wilson made a handful of plays against the San Francisco 49ers that he has never made his entire NFL career originally ...

A Tenderloin landmark, popular among San Francisco’s punks and writers, has closed its doors. Edinburgh Castle, the two-story ...

For the 49ers their health has become a greater concern than their preseason performance. They just need to make sure they ...

The San Francisco 49ers could cut ties with wide receiver Brandon Aiyuk depending on his performance following his return ...

For a moment during Saturday's preseason game against the Las Vegas Raiders, it seemed as if the San Francisco 49ers had ...

Today's Raiders-49ers game featured an iconic name in San Francisco franchise history recording his first reception.

Saturday, August 16thTime: 4:00 p.m. ETTV Channel: NFL NetworkLive Stream: fuboTV (watch for free) The San Franci ...

The San Francisco 49ers will face the Las Vegas Raiders in week 2 of the NFL preseason on Saturday at Allegiant Stadium.

The Las Vegas Raiders host the San Francisco 49ers at Allegiant Stadium with kickoff set for 4 p.m. ET on NFL Network, with ...

Former San Francisco 49ers quarterback Sam Darnold reflected on his one-year tenure with the organization. Now the starting quarterback for the Seattle Seahawk ...

The San Francisco 49ers have some depth concerns at the receiver position, but they recently tried to trade for a solution.

The 49ers lost another player to season-ending injured reserve, as a running back has suffered a devastating injury.