TMC207 inhibits the proton pump of mycobacterial ATP synthase, a critical enzyme in the synthesis of ATP for Mycobacterium tuberculosis. Resistance is achieved through mutations at position 63 or ...

Scientists have developed oral nanorobots that target damaged heart tissue, deliver energy, and repair mitochondrial function ...

They screened thousands of compounds and found one that blocked ATP synthase—TB’s essential power source—and stopped its growth. This initial discovery was then refined by Dr Jerome ...

While a comprehensive cure-all to these neurological conditions is unlikely, scientists are making headway into understanding their fundamental characteristics with the hope of preventing or ...

Neurodegenerative diseases like Alzheimer's, Parkinson's, and ALS (amyotrophic lateral sclerosis) are debilitating conditions ...