OBJECTIVE--This study aimed to develop a physiologically based pharmacokinetic model for acetone and to predict the kinetic behaviour of acetone in the human body with that model. METHODS--The model ...

Organoids, miniaturized, stem cell-derived versions of human organs, are revolutionizing biomedical research by offering ...

It is used during pregnancy to reduce the risk of HIV transmission to the child. The aim of this work is to use a Physiologically-Based Pharmacokinetic (PBPK) model for prediction of maternal and ...

Approaches such as population pharmacokinetics (popPK), exposure-response analysis, and physiologically based pharmacokinetic ... and simulation employs algorithms ideally suited to leverage ...

Approaches such as population pharmacokinetics (popPK), exposure-response analysis, and physiologically based pharmacokinetic (PBPK) modeling are now widely used to support regulatory submissions ...

Simulations Plus, Inc. (Nasdaq: SLP) ("Simulations Plus"), a leading provider of cheminformatics, biosimulation, ...

It is the most widely used QST modeling software for DILI prediction and is utilized as a source of QST modeling-based data assessed ... and a new T-cell model that allows for better understanding ...

The U.S. Food and Drug Administration (FDA) recently announced it plans to phase out animal testing in the development of monoclonal ...

The new model, which is supposedly a very stripped-down Model Y, was supposed to debut in the first half of this year but now might not come until late 2025 or early 2026, states the report.

On Thursday, the AI lab announced that it has started a research program to investigate — and prepare to navigate — what it’s calling “model welfare.” As part of the effort, Anthropic ...