After a median follow-up of 10 years, more than one-third of patients with large B-cell lymphoma and nearly half of patients ...
Approximately 30%-50% of patients with relapsed or refractory B-cell non-Hodgkin lymphomas have achieved durable remissions with CAR T-cell therapies targeting CD19 over follow-up periods of up to 5 ...
Lymphoma-free survival exceeding 5 years in early recipients of the cellular therapy ...
Target selection leverages DLL3’s high tumor-surface expression in SCLC/LCNEC and limited normal-tissue expression, while dnTGFBR2 “armoring” aims to blunt TGF-β–mediated T-cell suppression. Dose ...