Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

Researchers from CIIMAR and the University of Helsinki have discovered a new biochemical modification in natural ...

Researchers discovered that a tiny structural feature of the enzyme GPX4 helps keep neurons safe. A rare mutation removes ...

That’s the big idea behind Zymosense, “The Nanoassay Company,” a startup that’s spinning off technology developed in the lab ...

The protein, reverse transcriptase, has become an essential tool for making DNA copies of RNA.

RFdiffusion2, RFdiffusion3, and Riff-Diff each solve different structural problems in computational enzyme design ...

The OT-I mouse T-cell receptor (TCR) is thought to perfectly discriminate between lower-affinity self- and higher-affinity foreign antigen-MHC complexes. This study shows OT-I TCR to exhibit imperfect ...

Multienzyme complexes are stable assemblies of more than one enzyme, generally involved in sequential catalytic transformations. These are distinct from a multienzyme polypeptide, in which multiple ...

Bacteria that produce many antibiotics use a surprising self-poisoning system to coordinate development. Sensing a key signal triggers a pathway creating toxic byproducts, but only those bacteria able ...