Chromatin fractions enriched with certain histone modifications were captured by antibodies (H3K27me3 (CST, C36B11), H3K4me3 (Abcam, ab213224) and IgG) and released by protease digestion. RT-qPCR was ...

EZH2 is a histone methyltransferase. That means it places chemical marks on DNA-packaging proteins called histones. These marks can either silence or activate nearby genes. In healthy people ...

Department of Emergency, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Ministry of Education), West China Second University Hospital, Sichuan University, Chengdu, China ...

This important paper describes the regulatory pathway of rRNA synthesis by Meioc-Piwil1 in germ cell differentiation in zebrafish. Using the molecular genetic and cytological approaches, the authors ...

Mount Sinai Center for Therapeutics Discovery, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States Department of Pharmacological Sciences, Icahn School of Medicine at ...

State Key Laboratory of Tropical Oceanography, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou ...