Appropriate organization of three germ layers—endoderm ... germ layers in this in vitro embryo model. Propidium iodide (PI, Sigma) was used to label apoptotic ESCs. Colonies after 5 days ...

The findings, published today in Nature, uncover fundamental knowledge about the processes that programme cell fate in the early embryo to ... The three layers (called germ layers) established ...

Because these blastoids only use ESCs derived from the epiblast, which becomes the embryo proper with germ layers, they model embryonic development’s pre-implantation period, up to seven days post ...

This finding is unexpected because the traditional view holds that liver cells and endothelial cells are supposed to emerge from different germ layers. The long-held consensus was that an embryo ...

A study published today in the journal Developmental Cell uncovers new insights into how the heart forms during the earliest stages of embryonic development.

During the process of gastrulation, the germ layers are formed and then rearranged, which creates the internal and external parts of the developing embryo. Gastrulation occurs according to a ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilised egg, starts to ...

The heart and lungs develop from two distinct germ layers within the embryo, the mesoderm and endoderm, which must communicate with each other for the organs to form correctly. "My scientific ...

When the neural anlage develops, the germ layers of the ball-shaped embryo move in opposite directions. The mesoderm and endoderm -- also referred to collectively as mesendoderm - move to one pole ...

A study published today (September 11) in Nature Ecology & Evolution suggests that instead of two distinct germ layers, cnidarians may indeed have three. The authors show that the mesendoderm of the ...