This hypothesis is supported by the averaged NMR solution structure of the ETS ... Although most of the different DNA interactions between SAP-1 and Elk-1 map to the DNA recognition helix, the ...

They found an unexpected structure in a DNA repair protein called RAD52, which plays a key role in helping cancer cells survive. This breakthrough could help researchers design new drugs that ...

Get Instant Summarized Text (Gist) The DNA repair protein RAD52 has been found to adopt a unique double-ring structure when binding to DNA, which may aid in developing new cancer treatments. This ...

Their findings are published in Cell Reports Medicine in the paper, “Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity.” David Weiner, ...

The core binding factor β subunit (CBFβ) is the non-DNA binding subunit ... resolution solution structure of the CBFβ heterodimerization domain (residues 1–141), and map the binding site ...

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