A study led by the University of Cincinnati Cancer Center reveals how the MYC oncogene accelerates lymphoma growth through ...

Research from the University of Cincinnati reveals how the MYC oncogene alters PRPS enzymes, impacting redox homeostasis and ...

A study led by University of Cincinnati Cancer Center researchers sheds new light on the mechanisms by which a major oncogene ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

Method reveals unexpected behavior in molecular crowding during cell state transitions and suggests density as a biomarker for functional precision medicine.

Innovative delivery techniques, including high-tech nanoparticles and electroporationdevices, may convey more gene therapies into the clinic.

fbl-1 and fbl-2 are required for planarian homeostasis and regeneration. fbl-1 and fbl-2 display complementary expression patterns and functions in epidermal cell lineage development. fbl-1 and fbl-2 ...

This discovery could lead to new therapeutic approaches that not only strengthen beta cell function but also ... how beta cells regulate their insulin homeostasis," says Heiko Lickert.

Here, we summarize the current knowledge on the molecular landscape of cardiac fibroblasts, focusing on their dual role in promoting tissue homeostasis and modulating immune cell–cardiomyocyte ...