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I am a Higher Scientific Officer in the Translational Therapeutics Team at the ICR. My focus is on leveraging apoptotic pathways to combat therapy resistance and study immunogenic responses.
Professor Pearl's group seeks to understand the structural basis for assembly, specificity and regulation of the multi-protein complexes involved in the recognition, repair and signalling of DNA ...
These days, in the era of personalised medicine, whenever researchers discover a new cancer drug they are expected to show exactly how it works and to prove that it is exerting its therapeutic effect ...
Scientists have discovered a key protein that could be targeted with a drug to treat the most common and aggressive form of pancreatic cancer. The findings, published in Nature, show that blocking the ...
The overuse of CT scans could cause over 100,000 cases of cancer in the US – with almost 10,000 cases in children, researchers have warned. According to a new modelling study, published in the journal ...
Every day in the UK, about 1,000 people find out that they have cancer. Most of these people will end up sharing the news with family, friends and colleagues, from whom they will usually receive ...
Thousands of women with breast cancer could be spared unnecessary treatment, thanks to a simple test which can identify whether or not their cancer is likely to return – just two weeks after starting ...
Image: KRAS-mutated cancer cells. Credit Lisa Pickard / Louise Howell / ICR Researchers are set to to combine expertise in drug discovery, artificial intelligence (AI), and experimental cancer models ...
We share the story of a pioneering and collaborative research programme at the ICR, initiated in the late 1990s, that led to one of the first clinical-stage PI3K inhibitors, laying the foundation for ...
Last month, DeepMind published the much anticipated, detailed methodology underlying the latest version of AlphaFold – the UK-based science company’s powerful AI system that blew away its rivals in ...
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