The role of EGFR in KRASG12D-driven tumorigenesis was studied using mouse CRC organoids with KRAS-APC-TP53 mutations and ...

Mammary gland fibroblasts are highly plastic and transition through distinct states during development and disease. A new ...

Following this standard treatment regimen, the rodents develop recurrent tumors, establishing what is referred to as an ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. In early-stage estrogen receptor-positive (ER ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The identification of tumour-specific ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. This study presents and characterizes a Dnmt3a ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Genetic variation and 3D chromatin structure ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mycobacterium tuberculosis causes long-term ...

This cover highlights the article T-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses by Eleonora Sala, Maria Nelli, Matteo Iannacone, Mirela Kuka and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Defects in mitochondrial oxidative metabolism ...