Scientists have identified five specific blood proteins that can accurately predict a person's risk for developing a serious ...

Scientists have discovered a new type of cell in the liver that plays a critical role in repairing damage. These "leader ...

While organoids aim to mimic human organs, the liver's repertoire of complex functions – and thus the energy it needs to operate – have made it challenging for researchers to grow organoids that ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria allows us ...

In addition to the previous therapy with interferon-alpha, Hepcludex has recently become available as a drug that can effectively prevent HDV from entering liver cells. However, Hepcludex has no ...

Research in Mayo Clinic's Liver Disease Immunobiology Lab led by Petra Hirsova, Pharm.D., Ph.D., focuses on metabolic dysfunction-associated steatohepatitis.

Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ ...

A more recent approach is transplantation of mature liver cells, known as hepatocytes. “The problem is obtaining sufficient quantities of fully functioning hepatocytes,” says Ochiya.

When the gene malfunctions, fat accumulates in liver cells and triggers inflammation. Over time, this leads to fibrosis and scarring, which stiffens the liver. In severe cases, the disease ...

Multi-modal data integration of single-nuclei RNA and ATAC sequencing with spatial transcriptomics, provides new molecular insights into gene regulatory networks driving cell state transitions in ...

A multidisciplinary team from China has successfully transplanted a gene-modified pig liver into a human recipient ... with immunosuppressants. “T-cell activity was inhibited by antithymocyte ...

Most people have low levels of the AST enzyme. Damage to liver cells can cause the release of extra AST into the blood though, leading to higher levels of the enzyme. Doctors primarily use the AST ...