In vitro tests have demonstrated that second-generation antihistamines have improved H 1-receptor specificity ... Investigational models like the histamine-induced skin wheal-and-flare model ...

Vogt produce histamine synthetically by removing the ... 1972—James Black discovers the H2 receptor and characterizes its antagonist, burimamide. 1999—Researchers at a subsidiary of Johnson ...

Abstract and Introduction Predicting and Establishing the Clinical Efficacy of a Histamine H Application ... for evaluating the efficacy of the H 1-receptor antagonist desloratadine.