Vogt produce histamine synthetically by removing the ... 1972—James Black discovers the H2 receptor and characterizes its antagonist, burimamide. 1999—Researchers at a subsidiary of Johnson ...

Abstract and Introduction Predicting and Establishing the Clinical Efficacy of a Histamine H Application ... for evaluating the efficacy of the H 1-receptor antagonist desloratadine.

The mechanism of action of fentanyl is best described by its agonist interaction with the opioid µ-receptor. These sites of interaction ... and weaker allergenic (histamine mediated) activity ...