With reports of the first human death from bird flu in the US, some Americans are feeling an uncomfortable flashback to the early days of Covid-19, when infectious disease experts were talking about a new virus that was sending people to the hospital with respiratory infections.

Louisiana has reported the first U.S. fatality from avian influenza. Most of the country’s human cases have been mild

The case in Louisiana is the first human death from bird flu in the U.S. during this current outbreak, but there was a death in Mexico back in May 2024 in a patient with no known exposure to farm animals. The case, much like the patient in Louisiana, was in a person with other underlying conditions, though it’s not clear what those may have been.

The experiment of whether H5 can ever be successful in human populations is happening before our eyes,” Seema Lakdawala, a flu virologist at Emory University, told me. “And we are doing nothing to stop it.

In its announcement this week of the first human death from bird flu in the United States, health officials in Louisiana were quick to note that the patient was over age 65 and “reported to have underlying medical conditions.

Any time a person catches H5N1, or bird flu, their infection is a chance for the virus to mutate in the wrong direction. When someone dies from the bird flu—as an elderly Louisiana man did on Jan. 6,

The bird flu virus circulating among cows, poultry and wild birds isn't yet a threat to the general public, but experts say if and when that will change is impossible to predict — and that if things do get bad,