Saarvienin A, a newly identified glycopeptide antibiotic from Amycolatopsis, exhibits strong activity against multidrug-resistant bacteria, including vancomycin-resistant Enterococcus and MRSA.

The bacterium belongs to the actinobacteria group, known for producing clinically important antibiotics such as vancomycin and rifamycin. Initial extracts from the strain demonstrated potent ...

Despite over 60 years of clinical use, there is still debate on the drivers, modifiers, and time-course of the kidney injury associated with vancomycin. Drug-induced kidney injury results in ...