ALTHOUGH abnormal bleeding has been known to occur as a complication of renal failure at least since the time of Bright (1827) surprisingly little attention has been paid to this problem. A recent ...

It has been known for many decades that uremic bleeding and platelet dysfunction put patients at increased risk of general bleeding. The exact mechanism by which the risk is increased remains largely ...

Study of the bleeding tendency in uremia in 26 subjects, 10 of whom were bleeding, showed platelet counts and plasma coagulation factors to be normal. There was a significant inverse correlation ...

In advanced renal failure, bleeding diathesis is recognized as a complication leading to serious haemorrhagic events, including gastrointestinal bleeding and haemorrhagic pericardial effusion. Several ...

A potential treatment target has been discovered to prevent chronic kidney disease patients from developing blood clots without causing bleeding complications - an unwanted and perplexing side effect.

You have full access to this article via your institution. As pointed out by Mezzano et al., most of the studies used bleeding time as an end point to assess bleeding risk. We agree that this ...

Uremic bleeding in patients with chronic renal failure is extremely complex. One factor contributing to this complexity is the incomplete elucidation of the pathophysiology of the condition. As we do ...