TSC1 and TSC2 are tumor suppressor genes whose protein products, hamartin (TSC1) and tuberin (TSC2), negatively regulate cell growth in a variety of systems. In humans, heterozygous mutations in ...
Tuberous sclerosis complex (TSC)1 and TSC2 are tumor suppressors that inhibit cell growth and mutation of either gene causes benign tumors in multiple tissues. The TSC1 and TSC2 gene products form a ...
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