Biocatalytic asymmetric synthesis of chiral alcohols harnesses the remarkable selectivity of enzymes to convert prochiral ketones into optically pure alcohols under mild conditions. Chiral alcohols ...

Researchers at the Biocatalysis group led by Dr Francesco Mutti at the Van ‘t Hoff Institute for Molecular Sciences (University of Amsterdam) have developed a novel use of alcohol dehydrogenase (ADH) ...

Amides and thioesters are ubiquitous compounds in chemistry, used for the production of medicines, natural products, and advanced materials. Traditionally, their synthesis is a messy business, ...

Organic molecules are peppered with carbon-hydrogen bonds, and chemists have built up a fantastic toolbox of methods to break these bonds and put more useful functional groups in their place. This ...