A new CAR T-cell therapy attacks supportive cells in the tumor microenvironment that bear the surface protein, uPAR.
Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers like leukemia and ...
In 2021, the lab of chemical biologist and Nobel Laureate Carolyn Bertozzi, PhD, professor at Stanford University, characterized a new type of cell-surface protein, termed glycoRNAs, that form highly ...
Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a cell surface receptor ...
A new kind of medicine that destroys specific proteins on the surface of cells could lead to better therapies for conditions such as cancer. The approach, devised by Xin Zhou at the Dana-Farber Cancer ...
The FDA has granted Fast Track designation to ZW191, an antibody-drug conjugate (ADC) targeting folate receptor-α (FRα), for ...
To survive in the human bloodstream, the African trypanosome parasite wears a "cloak" made of proteins known as a variant ...
Protein surface serves as an important representation of protein structure, determining the biological functions. With the flourishing of deep learning, various descriptors for protein surface have ...