Heme is a coordination complex consisting of ... allowing the condensation of glycine with succinyl-CoA to form ALA and CO 2 in the mitochondrial matrix. ALA is subsequently transported to the ...

Further investigations revealed that this reduction of succinyl-CoA levels was at least in part caused by its overconsumption for the synthesis of heme, which is essential for mitochondrial ...

Treatments with vitamin B5 or another metabolite, succinyl-CoA, increased the maturation of red blood cells. Current treatments for MDS are often associated with reduced quality of life as well as ...

Further investigations revealed that this reduction of succinyl-CoA levels was at least in part caused by its overconsumption for the synthesis of heme, which is essential for mitochondrial ...