Studies that compare immune cell phenotype and function in psoriatic arthritis (PsA) versus psoriasis limited to cutaneous involvement (Pso) are scarce, yet critical to understand the pathogenesis of ...

Psoriasis plaques have a stubborn habit of returning to the exact same patches of skin, even after months or years of apparent remission. For the millions of people living with this chronic ...

Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

Immune cells are vigilant sentinels stationed at their tissue posts, such as the skin, lungs, or gut, or circulating in the bloodstream. Their presence and ability to quickly mobilize are key defenses ...

Clonally expanded CD8+ T cells are key drivers of alopecia areata, mediating epithelial cell death and immune infiltration. JAK inhibitors are approved for AA treatment, but recurrence is common, ...