Hypertrophic scarring affects a large proportion of patients following burns, trauma, or surgery and arises from prolonged fibroblast hyperactivity and excessive extracellular matrix accumulation.

Researchers reveal TGF-β1 promotes scar tissue formation and restricts recovery ...

As inflamed regions of the gut form scar tissue, the space within the gut lumen becomes smaller and more restricted, leading ...

Researchers discovered immune cell aggregates in the gut may signal blood vessel cells and fibroblasts to produce excess collagen, driving fibrosis in Crohn’s disease. The findings could guide ...

Researchers in the College of Medicine – Tucson’s Department of Surgery are uncovering new insights into how mechanical strain on cells affects healing. Researchers at the University of Arizona ...

A collaborative study reveals two kinds of scarring, dubbed hot and cold, in injured heart tissue, suggesting that treatments must take the type of scar into account Not all scars are created equal.

Not all scars are created equal. That's the conclusion of a new study by Weizmann Institute of Science researchers: They found that two distinct types of scars, referred to as "hot" and "cold," can ...

Researchers at the Earlham Institute, the University of Edinburgh and Heriot-Watt University analyzed gut cells to understand the drivers behind fibrosis, a common complication in Crohn's disease ...

RIT biomedical engineering researchers identify a protein that can reduce fibrosis and slow disease progression.