The Emmy winner originally went in to read for the part of Regina George, which eventually went ... ‘We think you’re more correct for Karen,'” she said. “So I was like, ‘Oh god, OK ...

Another user added: "Regina was always the main character in ... is played by Black actor Jaquel Spivey and Plastic member Karen Smith is now Karen Shetty, played by South Asian Avantika.

Amanda Seyfried first auditioned to play Regina George in Mean Girls for her first-ever movie role Amanda Seyfried says Blake Lively almost wound up playing Karen Smith in 2004's Mean Girls!

This elite group consists of Cady Heron, Gretchen Wieners, Karen Smith, and Regina George. The awesome foursome came up with some great lines... as did the rest of he cast. Take a look at the ...

Many of those unforgettable lines came from one of the movie’s most intimidating characters: Regina George ... quality into the character of Karen Smith. Seyfried nailed this part, convincingly ...

EW’s partners at The Take took a closer look at Tina Fey’s iconic comedy to dissect queen bee Regina George (Rachel ... Wieners (Lacey Chabert) and Karen Smith (Amanda Seyfried).

But ultimately, Seyfried was instead cast as Karen Smith, the pretty but unintelligent best friend who could do no wrong. Finding the perfect Regina George was critical, but Waters initially ...

When we last saw the “Mean Girls” crew, Cady Heron had learned a lesson and the “Plastics” -- Gretchen Wieners, Karen Smith and Regina George -- had split up and gone their separate ways.

Mean Girls cast real ages: find out how old Lindsay Lohan (Cady Heron), Rachel McAdams (Regina George), Amanda Seyfried (Karen Smith) and more were during filming. Mean Girls has just arrived on ...

recited lines from one of the lunchroom scenes from Mean Girls in which the Plastics — Regina, Gretchen and Karen Smith (played by Amanda Seyfried) — explain the rules of high school to Cady.

where Regina and her posse of Plastics — Cady Heron (Lindsay Lohan), Gretchen Wieners (Lacey Chabert), and Karen Smith (Amanda Seyfried) — strut through after school to greet Mrs. George ...

Its in the simple Regina George quotes that the essence of her character really comes out in Mean Girls. After lying to Cady about staying in, she says this to Karen (Amanda Seyfried) when the two ...