More information: Chuyao Fan et al, Bioorthogonal information storage in l-DNA with a high-fidelity mirror-image Pfu DNA polymerase, Nature Biotechnology (2021). DOI: 10.1038/s41587-021-00969-6 ...

Now his team has built a mirror version of the 775-amino acid Pfu DNA polymerase, which Zhu says is the largest functional protein to be chemically synthesized to date. In its natural form ...

These include Pfu DNA polymerase (from the archaea pyrococcus furiosus) which is ~4 times more stable than Taq DNA polymerase at 95°C (though exhibits limited processivity (< 20 bases ...

Archaeal family B DNA polymerases are uniquely able to recognize ... this pocket and have engineered specific mutations in the Pfu polymerase that confer the ability to read through template ...

Loop-mediated isothermal amplification (LAMP), a DNA amplification technique valued for its speed, specificity, sensitivity, ...

Structures of primases from the archaeon Pyrococcus furiosus (Pfu) 3 and from Escherichia coli 4 differ greatly from each other and are unrelated to known DNA polymerase structures. Structures of ...