Clin Drug Invest. 2007;27(8):509-531. Antiretroviral drugs (ARVs) can be divided into four different classes according to their modes of action: nucleoside or nucleotide reverse transcriptase ...

Antiviral nucleoside analogues represent a pivotal class of compounds that mimic physiological nucleosides and are enzymatically incorporated into viral genomes, thereby inhibiting viral polymerases ...

A vascular dilatation in the aorta can be life-threatening if it bursts. These so-called aortic aneurysms typically form in the same sites of the large blood vessel: either on the upper arch or in the ...

Clin Drug Invest. 2007;27(8):509-531. This review was supported by an educational grant from GlaxoSmithKline. GlaxoSmithKline played no role in the preparation or review of the manuscript, nor was ...

A team from the Wistar Institute has demonstrated the role of Parkin—a protein implicated in Parkinson's disease—in the body's innate immune response to cancer. Parkin is not expressed in several ...