Researchers from The University of Osaka find that chronic liver congestion is linked to severe liver diseases through a specific signaling pathway in liver sinusoidal endothelial cells - key cells ...

At a potluck, you ate the best chocolate chip cookie—golden-brown, thick and chewy. Unfortunately, you don't know who made the cookie to get the recipe from, so you decide to recreate it. Using ...

FDA proposes using a well-supported mechanistic rationale plus natural history comparators to generate substantial evidence when randomized trials are infeasible for ultra-rare populations.

Scientists have long been puzzled by how maturing red blood cells manage to produce all the hemoglobin they need to carry ...

The U.S. Nuclear Regulatory Commission (NRC) voted to approve the issuance of a new set of regulations for advanced reactor licensing—the long-awaited 10 CFR Part 53. The new rule crystalizes decades ...

High blood pressure, a leading cause of heart attack and stroke, affects nearly half of all adults in the United States. New research suggests a common type of high blood pressure may be caused by ...

On February 23, the FDA announced a new approval pathway designed to support the development of drugs for ultra-rare diseases. Often, treatments for ultra-rare diseases have difficulty meeting the ...