A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...

Scientists have long known that inherited neurodegenerative disorders, including Alzheimer's, Parkinson's or motor neuron ...

Researchers have changed the way to look at DNA. They show that DNA is much more than a linear sequence of building blocks; it has a 3D structure that influences the variation of human genome-wide ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

Scientists have created a new technique that can assess how mutations in the genome influence the packaging of DNA in cells. The genome is massive, and has to be carefully wrapped around proteins so ...

Much of pancreatic cancer’s evasive and deadly nature may come down to low levels of one gene. In A Nutshell Early detection, ...

A new long-read sequencing technique has helped researchers investigate how DNA mutations arise in a variety of contexts. A collaboration of researchers led by NYU Langone Health and NYU Grossman ...

In a new study, terrestrial bacteria-infecting viruses were still able to infect their E. coli hosts in near-weightless ...

A graph-based computational tool for detecting previously invisible genetic mutations has been developed. Researchers at the University of California, Los Angeles (UCLA; USA) and the University of ...