Thus, the involvement of different signalling pathways in the control of miRNA function should be studied. It is also highly likely that the mechanisms that control translation initiation will ...

This finding suggests that the noncanonical mechanism plays a significant role in the evolution of miRNA biogenesis and regulation. MicroRNAs (miRNAs) are tiny RNA molecules that play a crucial ...

An insightful molecular mechanism of how Microprocessor has been revealed by scientists: the DROSHA-DGCR8 complex, precisely determines cleavage sites on miRNA-containing primary transcripts ...

Chemotherapy failure is a consequence of acquired drug resistance which may potentially be due to multiple mechanisms including miRNA-mediated gene regulation. This review provides an overview of ...

In a recent study, researchers devised a strategy for genome-wide annotation of primary miRNA transcripts, providing extensive new annotations in human and mouse, and shedding light on mechanisms ...

On the technological front of molecular mechanism research, RNA Sequencing Technology and CRISPR/Cas9 have enriched our understanding of miRNA mechanisms and functions. By analyzing relevant data ...

miRNA mis-regulation contributes to multiple pathologies, underscoring its importance in tightly regulating gene expression. Essential to understanding the mechanisms by which any miRNA controls a ...

Cells became more fluorescent when genes that impacted the miRNA pathway were switched off, leading scientists to the discovery of the new phosphorylation mechanism involved in controlling miRNA ...

A couple of new studies, published online in the May 16 issue of Nature, discovered novel mechanisms for the gene silencing abilities of miRNA. Researchers from the European Molecular Biology ...

The guide strand of miRNA, which identifies and pairs with specific RNA bases, facilitates this complementary binding process. Through this mechanism, miRNA can inhibit protein formation, thereby ...

However, the underlying mechanisms and pathways regulated by ... "In our study, we focused on a molecule called miRNA-27a, which we found to exert an anti-inflammatory effect by suppressing ...