Here we show that the target sequence of two microRNAs, known to regulate genes in the class-III homeodomain-leucine zipper (HD–Zip) gene family of the flowering plant Arabidopsis, is conserved ...

Mature miRNAs can downregulate gene expression by pairing with ... method to better detect expression differences of miRNA family members in plants utilizing RT-PCR approach, and demonstrate ...

Their discovery added a new dimension to the understanding of complex gene regulatory networks in humans and animals alike. MicroRNA (miRNA ... in the genomes of plants and animals.

MicroRNAs (miRNAs) represent an extensive class of small endogenous RNAs which regulate gene ... miRNA biogenesis at each of these steps, thus proper miRNA homeostasis can be ensured. Although ...

In a new study, researchers in China present a rather striking finding: that plant miRNAs could make ... small RNAs to animals for in vivo gene silencing and miRNA gain-of-function studies.

The microRNA is located within a short segment called an intron, which gets spliced out of the gene when it is transcribed into mRNA. This means that whenever the gene is turned on, both the mRNA ...

Victor Ambros and Gary Ruvkun discovered microRNA, which the Nobel Assembly describes as "a fundamental principle governing how gene activity is regulated." The tiny microRNA molecules play a ...

They discovered microRNA, a new class of tiny RNA molecules that play a crucial role in gene regulation ... other small RNA molecules in both plants and animals, for example as a means of ...

In the present work, expression of certain miRNAs and their targets were investigated in three tobacco plants infected with Tobacco rattle virus (TRV) isolate Deb57 collected from Northern Poland in ...