A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ...

David Drew’s team then used the cryo-EM platform at SciLifeLab to visualize SLC35B1 in multiple conformations, revealing how it recognizes and transports ATP into the endoplasmic reticulum lumen. The ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy ...

The proteins that will be secreted by a cell are also directed to the ER during translation, where they end up in the lumen, the internal cavity, where they are then packaged for vesicular release ...

TorsinA is located predominantly in the contiguous lumen of the endoplasmic reticulum (ER) and nuclear envelope (NE) 5, and thought to be retained there by association with membrane-spanning ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into ...

A subsequent conversion to the carboxamide functionality, by an as-yet unknown enzyme, then allows translocation into the endoplasmic reticulum (ER) lumen. Once in the ER lumen, carboxamide form ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions—as enzymes ...

The endoplasmic reticulum plays a more important role in type 2 diabetes and its complications than previously believed, new research suggests. To make their discovery, scientists identified ...