The term complex aberrant is designated to describe karyotypes with multiple unrelated cytogenetic abnormalities. In acute myeloid leukemia (AML), 10–14% of all AML patients, and up to 23% among older ...
To our knowledge, this is the largest study to date to comprehensively evaluate NK-t-AML and provides a framework that may inform our understanding of NK-t-AML disease biology and could potentially ...
Nucleophosmin (NPM), a nucleocytoplasmic shuttling protein with prominent nucleolar localization, regulates the ARF-p53 tumor-suppressor pathway. Translocations involving the NPM gene cause ...
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