Combination therapy incorporating immune checkpoint blockade (ICB) with a PD-1/L1 inhibitor along with CTLA-4 inhibition or VEGF-targeted therapy has created a new standard of care with improved ...

Bcl6 regulates the lineage stability and suppressive function of Treg cells in head and neck squamous cell carcinoma ...

16,17 For these reasons, immunotherapy strategies utilizing both monotherapy and ICB combination approaches, as well as ICB therapy in combination with other rationale targeted therapies, have emerged ...

Researchers say, “It turns out SSRIs don’t just make our brains happier; they also make our T cells happier—even while ...

A widely used antidepressant drug could help the immune system fight cancer, according to a new UCLA research study.

This combination therapy robustly stunted tumor growth ... and activation of the Notch signaling pathway may respond better to immune checkpoint blockade (ICB). Incredibly, the MacPherson Lab recently ...

The researchers demonstrated that when used in combination with immune checkpoint ... of the TME and improve the antitumor efficacy of ICB therapy. Encouraged by the success of mRNA in COVID ...