Metabolic syndrome (MetS) is a multifaceted disorder that impacts approximately 20–25% of the global population. This syndrome encompasses a range of conditions, including obesity, type 2 diabetes ...

Hypothalamic obesity (HyOb) is a rare type of obesity caused by damage to the hypothalamus, the brain region that regulates hunger, metabolism, and energy balance. This damage disrupts your body’s ...

Please provide your email address to receive an email when new articles are posted on . Once-daily bivamelagon conferred significant reductions in BMI at 14 weeks. Participants receiving bivamelagon ...

FDA approval establishes setmelanotide as the first labeled option for acquired hypothalamic obesity, addressing a population estimated at ~10,000 in the US and characterized by severe hyperphagia.

Rhythm Pharmaceuticals, Inc. has announced that it received orphan drug designation from Japan's Ministry of Health, Labour and Welfare for setmelanotide, a treatment aimed at acquired hypothalamic ...

The widely used sugar substitute sucralose may affect “key mechanisms” in the brain’s hypothalamus responsible for appetite regulation, a small randomized crossover trial suggested. Compared with a ...