For this study, 73 examples of moderately and poorly differentiated prostatic adenocarcinoma and 46 examples of high-grade urothelial carcinoma were obtained from radical resection specimens.

The most common and clinically important lesions with 'large gland' morphology include high-grade prostatic intraepithelial neoplasia (HGPIN), PIN-like carcinoma, ductal adenocarcinoma ...

High-grade prostatic intraepithelial neoplasia (HGPIN) is the most likely precursor of prostatic adenocarcinoma according to virtually all available evidence. This lesion is characterized by ...

In the benign cohort, initial biopsies showed 37% of patients had ASAP with or without high-grade prostatic intraepithelial neoplasia (HGPIN), while 28% had HGPIN only, and 52% had neither ASAP or ...

Former US president Joe Biden has been diagnosed with prostate cancer, graded with a Gleason score of 9, a high-grade and ...

A novel blood test was more accurate than PSA screening for identifying patients with high ... prostate tissue, and elevations in PSA can only hint at the possible presence of underlying carcinoma.

If your doctor tells you that you have adenocarcinoma ... are given a low grade. If they don't look very much like normal cells (poorly differentiated), they are given a high grade.

Former US President Joe Biden has been diagnosed with an aggressive form of prostate cancer that has spread to his bones. The diagnosis highlights challenges in treatment, but offers hope through ...

The development of prostate cancer in both ... intraepithelial neoplasia [LGPIN] to high-grade prostatic intraepithelial neoplasia [HGPIN]) to adenocarcinoma. The angiogenic switch coincides ...

[29] Early morphometric and immunohistochemical studies showed that low-grade ... for high-molecular-weight cytokeratins (34βE12) or p63. By contrast, prostatic adenocarcinoma generally shows ...